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    218 - ׳¡׳¨׳˜׳�:
    (endometrial cancer) `
    `-
    (endometrial cancer) `
           (endometrial cancer)  `
    (endometrial cancer) `
    `-
    (endometrial cancer) `
           (endometrial cancer)  `
    , `.
    ` - . -6.8% , 2012 -723,000 . , , , . , , , -, ` ...
          ,  `.
    : , `.
    ` - . - , -, , -, . , 23,380 " 2014, -14,320 : , 1.4% " -2.4% . 6.4 100,000 ", 5 33.4%...
       :  ,  `.
    : , `.
    ` - . - , -, , -, . , 23,380 " 2014, -14,320 : , 1.4% " -2.4% . 6.4 100,000 ", 5 33.4%...
       :  ,  `.
    , `.
    ` - . . 55-64. -90% , . (germ cells) -5% , -30% . , . -20 , . ...
         ,  `.
    , `.
    ` - . . 55-64. -90% , . (germ cells) -5% , -30% . , . -20 , . ...
         ,  `.
    - ? `.
    ` - . Allison -30 , , . 1983 Allison -Cell , T . 1992 -Nature - Allison T -CD28 (signal) , "" (anergy) . 4 Allison -Science 1994, CTLA-4 T ...
     -          ?  `.
    - "
    `-
    - "
      -
    - HE4 Human epididymal protein 4: ? `.
    ` - . -ACS " 22,280 2012, 15,500 . -IARC 2012 Ferlay `, -4.7 50 , -29.6 50-64 . , -75% , , ...
      -  HE4  Human epididymal protein 4:      ?  `.
    Non-Hodgkin Lymphoma " ` `
    `-
    Non-Hodgkin Lymphoma " ` `
           Non-Hodgkin Lymphoma
    Non-Hodgkin Lymphoma " ` `
    `-
    Non-Hodgkin Lymphoma " ` `
           Non-Hodgkin Lymphoma
    Non-Hodgkin Lymphoma " `, `
    `-
    Non-Hodgkin Lymphoma " ` `
           Non-Hodgkin Lymphoma
    (HPV) , (oropharyngeal) `.
    ` - . (HPV) -200 , -, . -HPV , , . , HPV ( -80%), , 4 100 )...
       (HPV)     ,       (oropharyngeal)  `.
    - , `
    `-
    - , `
      -      ,  `
    - , `
    `-
    - , `
      -      ,  `
    BRCA1/BRCA2 , `.
    ` - . 2007 -Journal of Clinical Oncology, Chen - Parmigiani ֶָ-, -2 . BRCA1/BRCA2 . , , . , -90%, , .
            BRCA1/BRCA2   ,  `.
    : type 2
    ` -
    : type 2
        :  type 2
    , , `
    ` -
    , , `
     ,     ,  `
    pancreas ,
    `-
    pancreas ,
         pancreas   ,
    -
    -Giotrif () EGFR
      -
    Multiple Myeloma: , `
    ` -
    Multiple Myeloma: , `
      Multiple Myeloma:     ,  `
    Multiple Myeloma: , `
    `-
    Multiple Myeloma: , `
      Multiple Myeloma:     ,  `
    , `.
    ` - . , . 40 : 70 2-3 55 69 , 15-20 30 54 . . , ...
               ,  `.
    , `.
    ` - . , . 40 : 70 2-3 55 69 , 15-20 30 54 . . , ...
               ,  `.
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